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KMID : 0374919930140020223
Inje Medical Journal
1993 Volume.14 No. 2 p.223 ~ p.230
Epidermal Growth Factor Receptor Expression in Rat Fetal and Postnatal Epidermis



Abstract
This study was done to investigate the distribution and number of EGFR in the perinatal rat epidermis by using immunohistochemistry.
@ES The results were as follows:
@EN 1. In fetal epidermis EGFRs were observed throughout the whole layer of epidermis.
2. Light stained cells were observed through the whole layer of epidermis till 10-day of age and thereafter observed only in the basal layer, and especially strong positive reaction is observed at neonatal 1-day.
3. From these results the intense immunoreactivity for EGFR was observed at neonatal 1-day, which was supposed to be critical period for skin development.
KEYWORD
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